Medicines for high uric acid, such as allopurinol or probenecid, help reduce the production of uric acid or promote its elimination, and are indicated for the treatment of gout or gouty arthritis, or prevention of gout attacks.
Furthermore, other medications, such as colchicine, indomethacin, ibuprofen or prednisone, may also be indicated for acute attacks of gout, as they have anti-inflammatory action, helping to alleviate symptoms of pain and swelling in the joints. Know how to identify the symptoms of gout.
Remedies for high uric acid must be indicated by the rheumatologist, on an individual basis, after carrying out tests that measure the amount of uric acid in the blood and urine, as well as evaluating the symptoms and their severity.
11 remedies for uric acid
The main remedies that may be recommended by your doctor for uric acid are:
1. Alopurinol
Allopurinol is a medicine that helps reduce the levels of uric acid in the blood and urine, as it acts by inhibiting its synthesis, preventing it from being deposited in the joints or organs, and is indicated in cases of gout or kidney stones.
Furthermore, this medicine can also be indicated to prevent the appearance of kidney damage in people undergoing chemotherapy treatment for blood cancer, as in these cases, there is a greater risk of an increase in uric acid.
Allopurinol is available in the form of 100 or 300 mg tablets, as a generic or under the commercial name Zyloric, and is provided free of charge by the SUS or can be purchased in pharmacies or drugstores upon presentation of a medical prescription.
How to use: The initial dose for adults and children over 10 years of age is lower, to avoid the appearance of side effects, and it is generally recommended to take 100 mg of allopurinol per day, after a meal. In some cases, your doctor may recommend taking up to 900 mg per day. Find out how to take allopurinol.
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2. Probenecida
Probenecid is a uricosuric medicine that works by increasing the elimination of uric acid in the urine, which helps regulate and reduce uric acid levels in the body, and is recommended for the treatment of chronic gout or gouty arthritis.
In addition, probenecid may also be indicated for people with recurrent severe gout who experience serious side effects with the use of allopurinol.
How to use: The normally recommended starting dose for adults is 250 mg of probenecid orally, twice a day, for 1 week of treatment. The maintenance dose is 500 mg, twice a day, or as directed by your doctor. During treatment, you should drink plenty of water and avoid using acetylsalicylic acid, as it reduces the action of probenecid.
3. Sulfinpirazona
Sulfinpyrazone is another uricosuric medicine that increases the elimination of uric acid in the urine, indicated for the treatment of gout, gouty arthritis or gouty tophi, helping to prevent acute attacks of gout.
How to use: the recommended initial dose is 200 to 400 mg orally, divided into 2 doses per day. This dose can be increased or decreased by the doctor after 1 week, depending on the response to treatment. The tablets should be taken with a meal or milk.
4. Colchicine
Colchicine is an anti-gouty medicine that can be indicated for the treatment or prevention of acute attacks of gout in cases of chronic gouty arthritis, as it has anti-inflammatory action, relieving pain, swelling and inflammation of the joints.
This medicine can be found in the form of 0.5 mg or 1 mg tablets, as the generic “colchicine” or under the trade names Colchis, Cixin, or Cocichimil, for example.
How to use: To prevent acute attacks of gout, the recommended dose is 1 tablet of 0.5 mg, 1 to 3 times a day, according to medical advice. For the treatment of acute crises, the initial dose is 0.5 mg to 1.5 mg, followed by 1 tablet at intervals of 1 hour or 2 hours, until pain relief occurs.
5. Indomethacin
Indomethacin is a potent non-steroidal anti-inflammatory drug that may be indicated for the treatment of acute attacks of gout or acute gouty arthritis, as it helps to relieve pain and swelling in the joints, caused by high uric acid that can be deposited in the joints. .
This remedy is found under the trade name Indocid, in the form of tablets with 25 or 50 mg of indomethacin, and treatment must be started within 48 hours of the onset of gout attack symptoms, in order to be more effective in controlling gout. the symptoms.
How to use: the recommended dose of indomethacin for adults is generally 50 mg, 3 times a day, taken after a meal, for 5 to 7 days, according to medical advice. See how to take indomethacin.
6. Ibuprofen
Ibuprofen is a non-steroidal anti-inflammatory that can be used to relieve acute attacks of gout, with symptoms of pain and swelling in the joints caused by the deposit of uric acid in the joints.
This medicine can be found in the form of tablets, drops, gelatin capsules or oral suspension, with the trade names Advil, Alivium, Buscofem or Ibuprotrat, for example.
How to use: The dose of ibuprofen for adults normally indicated for acute attacks of gout is 600 to 800 mg, 3 times a day, for 5 to 7 days, according to medical advice. Learn how to take ibuprofen correctly.
7. Naproxen
Naproxen is another anti-inflammatory indicated for the treatment of acute attacks of gout.
This medicine can be found in the form of tablets, as a generic under the name “naproxen sodium” or under the trade names Flanax, Naxotec, Nexflen or Naprox, for example.
How to use: the normally recommended dose is 500 mg of naproxen, twice a day, for 5 to 7 days of treatment.
Other non-steroidal anti-inflammatory drugs that may be recommended by your doctor for gout attacks are meloxicam, diclofenac or celecoxib, for example.
8. Prednisone
Prednisone, as well as prednisolone, are oral corticosteroids that can be indicated for the treatment of gout attacks, in people who have contraindications to the use of non-steroidal anti-inflammatory drugs or colchicine, or who have kidney failure.
How to use: The recommended initial dose of prednisone or prednisolone for acute attacks of gout is 30 to 40 mg, once a day, administered in a single dose or divided into two doses. This dose must be reduced by the doctor after the crisis improves, and treatment generally lasts 7 to 10 days. Learn how to take prednisone and prednisolone correctly.
9. Methylprednisolone
Methylprednisolone is an injectable corticosteroid with powerful anti-inflammatory action, which can be applied by the doctor directly to the joint with gout or gouty arthritis, in cases of acute attacks.
Furthermore, this medicine can be indicated for application directly to the muscle in people who have contraindications for injection into the joint or who cannot take oral corticosteroids.
How to use: The dose of methylprednisolone for application to the joint varies according to the affected joint and the severity of the symptoms. Likewise, the dose for application to the muscle varies according to the severity of the symptoms and must be indicated by the doctor.
10. Febuxostate
Febuxostat may be recommended by a doctor to prevent an increase in uric acid in people with gout, especially in people who cannot take allopurinol or when allopurinol is no longer effective in reducing uric acid levels.
How to use: The recommended dose of febuxostat is 1 tablet of 80 mg, once a day, taken before or after a meal. After 2 to 4 weeks of treatment, if the uric acid in your blood has not reduced to less than 6 mg/dL, your doctor may consider increasing the dose to 120 mg per day.
11. Rasburicase
Rasburicase is an enzyme indicated for the treatment or prevention of an increase in acute uric acid in the blood, to prevent the emergence of kidney failure, or kidney failure, in people with blood cancer, such as leukemia or lymphoma, for example.
Furthermore, this medicine is also indicated to prevent tumor lysis syndrome in people undergoing chemotherapy treatment for blood cancer.
Rasburicase, found in hospitals under the trade name Fasturtec, works by breaking down uric acid, preventing crystals from being deposited in the kidneys, preventing kidney deterioration and kidney failure.
How to use: rasburicase must be applied intravenously, that is, directly into the vein, by a nurse at the hospital, under medical supervision, and the normally recommended dose is 0.2 mg per kg of body weight, per day.
home remedy for uric acid
The best home remedy for high uric acid is to change your diet, which should be done by avoiding the consumption of alcoholic beverages and soft drinks, and foods rich in purines, such as red meat, fish or seafood, for example. See what the diet for high uric acid should be like.
Furthermore, it is important to lose weight and drink plenty of water a day, in order to keep the body hydrated, as it helps to reduce the frequency of gout attacks.
